Dehydroepiandrosterone, more commonly known as "DHEA" and its sulfated
form dehydropiandrosterone sulfate (DHEA-S) are endogenous steroids, having
a wide variety of biological and biochemical effects. Essentially, DHEA
can be called the adrenal stress, immunity and longevity hormone.
- anti-aging effects
- significant improvement of performance in the aged
- regulation of lean muscle mass production
- fat "burning"
- anti-depressant effects
- increased cognition
- memory and learning
- post menopausal benefits
In a study done in 1994, by Morales, Nolan, Nelson and Yen1,
82% of the 17 women were found to show an increased sense of well-being
after 12 weeks of administration. Well-being was reported as improved
quality of sleep, better relaxation, increased energy, and better ability
to handle stress. No difference was noted in libido, but 5 of the 17 did
show improvements in preexisting joint pains and mobility during DHEA
therapy at 50.mg per day. Most women and men above 40 years of age would
benefit by using 25 to 50 mg per day in several ways.
Another study done by Dr. Cranton, M.D. showed that in women, correct
levels of DHEA can convert into testosterone as the body needs, but men
do not experience much conversion of DHEA into testosterone. In fact,
after monitoring patients over 5 years, he showed that once the dose restored
the DHEA to normal levels, energy levels increased, skin became thicker
and moister, sleep was better and patients awakened rested. The patients
felt 10 years younger and had significantly increased sex drive. At the
pharmacy we have found that both men and women on the proper dose range
of our product do very well and have less ups and downs as we help them
fine-tune their natural "human identical" doses to fit them best.
Many women also require testosterone in the form of creams, gels, or
sublinguals in order to fully balance their hormones, restore their libido
and eliminate minor depression. In order to obtain a baseline reading
it is advised to do a saliva or blood test before using hormones and periodically
thereafter to check levels and keep them in range. When using the testosterone
creams or gels to increase libido, we always suggest application to the
area behind the knee continuing down the back of the calf and up the back
of the thigh. If it causes any unwanted hair growth, then this is an area
that can be shaved. Lastly, the testosterone "thick" gel 2% can be used
locally, with directions as follows: Apply a small amount (Lentil pea
size) to the clitoris and the surrounding area about one half hour before
bedtime each night. This dose form is used by thousands of women with
much reported success. Sometimes it is necessary to use two of the above
forms in combination therapy to achieve the desired effects.
Effects of Replacement Dose of Dehydroepiandrosterone in Men and Women
of Advancing Age. Arlene J. Morales, John J. Nolan, Jerald C. Nelson,
and Samuel S. C. Yen Department of Reproductive Medicine, University of
California School of Medicine, LaJolla, California 92093-0802; and Nichols
Institute Reference Laboratories, San Jaun Capistrano, California 92690.
(J. Clin Endocrinol Metab 78:1360-1367, 1994)
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