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Revival Soy Doctor  

  



Revival Soy Doctor Q&A's
Name: helga

Question:
Hi, I am interested if Revival soy would it be benefical for post menopause and when also using progesterone cream. I have been reading some articles where it was suggested that consuming soy would make your thyroid under active. Is there any truth in that? Thank you.

Answer:
Hello Helga,

Thank you for your question.

Before we get started, please read the following: We do not give medical advice. We provide nutritional information regarding Revival Soy products and information available in the public domain for the uses of soy. We advise you to discuss your personal medical issues with your physician. I hope our information will be helpful to you.

How will Revival Soy help menopausal or Postmenopausal women?

Many studies now show benefits of soy for menopausal symptoms:
http://www.revivalsoy.com/whysoy/article.html?article=menopause&pid=3000

The National Institutes of Healthís (U.S. Government) Medical Encyclopia lists ìfewer menopausal symptomsî as a potential benefit of soy:
http://www.nlm.nih.gov/medlineplus/ency/article/007204.htm

Revival Soy was created by Dr. Tabor to help his own mother handle midlife. You can read her story at http://www.revivalsoy.com/home/about/index.html?pid=3000

Scientists became very interested in soy's potential role for menopause support after demographic studies revealed that only 9% of women living in Asia, where the diet is rich in soy, experienced hot flashes during midlife, in contrast to almost 80ñ90% of Western women who suffer through menopause.

Many scientists feel that soy isoflavones, which are similar to the body's estrogen in structure, may support health by lightly binding to estrogen receptors, thus, producing some of the benefits of estrogen without negative side effects.

Because soy may support menopause, energy, bone and heart health, many doctors now recommend soy as a safe, effective dietary supplement to help women support a healthy midlife transition and beyond.

When can I expect results?
http://www.revivalsoy.com/whysoy/expect.html?pid=3000

Thousands of doctors, dietitians and healthcare professionals have
recommended Revival Soy to people who can benefit from adding soy protein
and soy isoflavones to their daily diets.
http://www.revivalsoy.com/whyrevival/recommended.html?pid=3000

Menopause Success Stories
http://www.revivalsoy.com/community/testimonials/index.html?pid=3000

Soy and Bone Health
http://www.revivalsoy.com/whysoy/article.html?article=bone&pid=3000

Will soy protein affect my thyroid function?

The FDA has rejected claims that soy adversely affects the thyroid due to lack of evidence. (Reference 1).

Multiple human and animal studies recently published have shown that soy protein does not harm thyroid function (see medical references 2 - 13 below).

It is puzzling why some dairy groups, and their friends, refuse to publish this positive new research about soy and thyroid health. The dairy industry has sued the soy industry over the term ìsoymilkî, so it appears this is a ësmear campaigní against soy solely due to financial greed (soymilk is taking market share away from dairy milk sales).

Please pass this information along to your family, friends and doctor.

MEDICAL REFERENCES:
1. US FDA says it weighed soy concerns versus benefits. By Lisa Richwine
WASHINGTON (Reuters) - U.S. health regulators weighed concerns that soy
products might be harmful but decided soy's positive effects justified touting its benefits to consumers, a Food and Drug Administration official said Monday.

The agency comment came in response to published remarks from two FDA scientists that eating soy might cause health problems, particularly if given daily to infants in soy milk formulas.

Drs. Daniel Doerge and Daniel Sheehan, the FDA scientists, have spoken to media organizations to warn that infants given soy formula might grow up t develop fertility problems.

They also worry that eating soy regularly might increase the risk of breast cancer in women and brain damage in men. Their most recent comments were published in Britain's Observer newspaper Sunday.

FDA officials considered the scientists' views and those of other critics before announcing last October that they would permit manufacturers to advertise that eating soy could help adults cut their risk of heart disease.

ìWe are well aware of the concerns, but we did balance those concerns with the other positive effects,î an FDA official said in an interview Monday.

The FDA reviewed scientific studies on soy before concluding that adults who consume 25 grams of soy protein per day could see a ìsignificantî lowering of cholesterol, which would lower their risk of heart disease. High cholesterol is a major risk factor for heart disease, the leading killer of
Americans.

Critics told the FDA soy could cause harm because it contains a chemical similar to the female hormone, estrogen,that might disrupt normal hormone levels and impair development. Some warned about the possibility of cancer, impaired fertility or thyroid problems.

The FDA said the concerns were not supported by conclusive scientific research. While chemicals in soy do exert hormonal effects, the impact is ìvery limitedî and much lower than that of natural or synthetic estrogens, the FDA said when it announced it would permit the soy health claim.

Concerns that soy infant formula could be harmful were ''speculative'' pending the outcome of definitive research, the agency said.

Critics who worry about the effects of soy infant formula recommend that it be used only when no alternatives exist.

A farmer-supported group said Monday concerns about soy's health effects were not new but were not widely held.

ìThe overwhelming body of published peer-reviewed scientific evidence shows soy has numerous health benefits,î said Michael Orso, a spokesman for the United Soybean Board.

17:23 08-14-00
Copyright 2000 Reuters Limited. All rights reserved.

2. SOY ISOFLAVONES DO NOT HAVE AN ANTI-THYROID EFFECT IN POSTMENOPAUSAL WOMEN OVER 64 YEARS OF AGE. B. Bruce. G. A. Spiller and L. Holloway. Health Research and Studies Center, Los Altos, CA 94022 and Palo Alto V.A. Health Care System, Palo Alto, CA 94034. Experimental Biology 2000, San Diego, CA April 15-18, 2000.

Studies in animals, in vitro, and infants using soy-based formulas have suggested a possible anti-thyroid effect of soy. In a randomized, double blind, placebo-controlled study, we investigated the effect on thyroid function of a concentrate supplying 90 mg of soy isoflavones in 38 postmenopausal women, aged 64-83 years old, not on hormone replacement therapy (HRT). Thyroid stimulating hormone (TSH), thyroxine (T4) and triiodothyronine (T3) were measured before supplementation (BS) and after 90 and 180 days.

These results suggest that there appears to be no anti-thyroid effect of soy isoflavones over six months in postmenopausal women not on HRT. Supported by a grant from Archer Daniels Midland Company.

3. Soy isoflavones exert modest hormonal effects in premenopausal women. Duncan AM, Merz BE, Xu X, Nagel TC, Phipps WR, Kurzer MS.
Department of Food Science and Nutrition, University of Minnesota, St. Paul 55108, USA. J Clin Endocrinol Metab 1999 Jan;84(1):192-7.

Soy isoflavones are hypothesized to be responsible for changes in hormone action associated with reduced breast cancer risk. To test this hypothesis, we studied the effects of isoflavone consumption in 14 premenopausal women. Isoflavones were consumed in soy protein powders and provided relative to body weight (control diet, 10 +/- 1.1; low isoflavone diet, 64 +/- 9.2; high isoflavone diet, 128 +/- 16 mg/day) for three menstrual cycles plus 9 days in a randomized cross-over design. During the last 6 weeks of each diet period, plasma was collected every other day for analysis of estrogens, progesterone, LH, and FSH. Diet effects were assessed during each of four distinctly defined menstrual cycle phases. Plasma from the early follicular phase was analyzed for androgens, cortisol, thyroid hormones, insulin, PRL, and sex hormone-binding globulin. The low isoflavone diet decreased LH (P = 0.009) and FSH (P = 0.04) levels during the periovulatory phase. The high isoflavone diet decreased free T3 (P = 0.02) and dehydroepiandrosterone sulfate (P = 0.02) levels during the early follicular phase and estrone levels during the midfollicular phase (P = 0.02). No other significant changes were observed in hormone concentrations or in the length of the menstrual cycle, follicular phase, or luteal phase. Endometrial biopsies performed in the luteal phase of cycle 3 of each diet period revealed no effect of isoflavone consumption on histological dating. These data suggest that effects on plasma hormones and the menstrual cycle are not likely to be the primary mechanisms by which isoflavones may prevent cancer in premenopausal women.

4. Modest hormonal effects of soy isoflavones in postmenopausal women. Duncan AM, Underhill KE, Xu X, Lavalleur J, Phipps WR, Kurzer MS.
Department of Food Science and Nutrition, University of Minnesota, St. Paul 55108, USA. J Clin Endocrinol Metab 1999 Oct;84(10):3479-84

Soy isoflavones have been hypothesized to exert hormonal effects in postmenopausal women. To test this hypothesis, we studied the effects of three soy powders containing different levels of isoflavones in 18 postmenopausal women. Isoflavones were consumed relative to bodyweight [control: 0.11 +/- 0.01; low isoflavone (low-iso): 1.00 +/- 0.01; high isoflavone (high-iso): 2.00 +/- 0.02 mg/kg/day] for 93 days each in a randomized crossover design. Blood was collected on day 1 of the study (baseline) and days 36-38, 64-66, and 92-94 of each diet period, for analysis of estrogens, androgens, gonadotropins, sex hormone binding globulin (SHBG), prolactin, insulin, cortisol, and thyroid hormones. Vaginal cytology specimens were obtained at baseline and at the end of each diet period, and endometrial biopsies were performed at baseline and at the end of the high-iso diet period, to provide additional measures of estrogen action. Overall, compared with the control diet, the effects of the low-iso and high-iso diets were modest in degree. The high-iso diet resulted in a small but significant decrease in estrone-sulfate (E1-S), a trend toward lower estradiol (E2) and estrone (E1), and a small but significant increase in SHBG. For the other hormones, the few significant changes noted were also small and probably not of physiological importance. There were no significant effects of the low-iso or high-iso diets on vaginal cytology or endometrial biopsy results. These data suggest that effects of isoflavones on plasma hormones per se are not significant mechanisms by which soy consumption may exert estrogen-like effects in postmenopausal women. These data also show that neither isoflavones nor soy exert clinically important estrogenic effects on vaginal epithelium or endometrium.

5. J Med Food. 2003 Winter;6(4):309-16. Isoflavone supplements do not affect thyroid function in iodine-replete postmenopausal women. Bruce B, Messina M, Spiller GA. Division of Immunology & Rheumatology, Department of Medicine, Stanford University, Palo Alto.

Despite the safety review conducted by the U.S. Food and Drug Administration in the process of awarding a health claim for the cholesterol-lowering properties of soy protein, concerns about the possible goitrogenic effects of soybean isoflavones persist. Concerns are based primarily on in vitro research, animal studies, and older reports of goiter in infants fed soy formula not fortified with iodine. In a randomized, double blind, placebo-controlled study, we investigated the effect on thyroid function of a daily supplement containing 90 mg (aglycone weight) of total isoflavones/day versus placebo in 38 postmenopausal women, 64-83 years old, not on hormone replacement therapy. Serum thyroid-stimulating hormone (TSH), thyroxine (T4), and triiodothyronine (T3) were measured at baseline and after 90 and 180 days. In the supplement group, at baseline and 6 months, TSH (micro U/ml), T4 (nM), and T3 (nM) levels (mean +/- SE) were 3.00 +/- 0.44, 149.00 +/- 5.04, and 1.53 +/- 0.13, respectively, and 3.49 +/- 0.52, 154.52 +/- 2.09, and 1.78 +/- 0.12, respectively. In the control group, levels at baseline and at 6 months were 3.35 +/- 0.51, 145.39 +/- 6.69, and 1.55 +/- 0.18, respectively, and 3.63 +/- 0.57, 153.77 +/- 6.64, and 1.75 +/- 0.10, respectively. Intragroup differences for all three measures were statistically indistinguishable at 6 months, and levels were similar between the isoflavone supplement and placebo groups at each measurement. These results indicate that in this group of healthy iodine-replete subjects, soy isoflavones do not adversely affect thyroid function.

6. Am J Clin Nutr. 2002 Jan;75(1):145-53. Effect of soy protein on endogenous hormones in postmenopausal women. Persky VW, Turyk ME, Wang L, Freels S, Chatterton R Jr, Barnes S, Erdman J Jr, Sepkovic DW, Bradlow HL, Potter S.Division of Epidemiology and Biostatistics, the School of Public Health, the University of Illinois at Chicago, USA.

BACKGROUND: The long-term clinical effects of soy protein containing various concentrations of isoflavones on endogenous hormones are unknown. OBJECTIVE: We examined the effects of ingestion of soy protein containing various concentrations of isoflavones on hormone values in postmenopausal women. DESIGN: Seventy-three hypercholesterolemic, free-living, postmenopausal women participated in a 6-mo double-blind trial in which 40 g protein as part of a National Cholesterol Education Program Step I diet was provided as casein from nonfat dry milk (control), isolated soy protein (ISP) containing 56 mg isoflavones (ISP56), or ISP containing 90 mg isoflavones (ISP90). Endogenous hormone concentrations were measured at baseline and at 3 and 6 mo. RESULTS: The concentration of thyroxine and the free thyroxine index were higher in the ISP56 group, and the concentration of thyroid-stimulating hormone was higher in the ISP90 group than in the control group at 3 and 6 mo (P < 0.05). Triiodothyronine was significantly higher in the ISP90 group only at 6 mo. Thyroxine, free thyroxine index, and thyroid-stimulating hormone at 6 mo were inversely associated with measures of baseline estrogenicity. No significant differences were found for endogenous estrogens, cortisol, dehydroepiandrosterone sulfate, insulin, glucagon, or follicle-stimulating hormone after baseline hormone values were controlled for. CONCLUSIONS: This study does not provide evidence that long-term ingestion of soy protein alters steroid hormone values, but it suggests that soy protein may have small effects on thyroid hormone values that are unlikely to be clinically important. The thyroid effects are, however, consistent with previous findings in animals and highlight the need for future research investigating possible mechanisms of action.

Will soy protein interfere with any of my prescription medications?

The FDA has not issued any drug interaction warnings for soy protein. However, due to the large number of new prescription medications on the market, we recommend that you simply call your pharmacist or medical doctor if you are taking prescription medications to check for any interactions.

The makers of SynthroidÆ, a thyroid medication, recommend eating certain foods, including those containing calcium, walnuts and soy, four hours apart from taking Synthroid.

Revival Soy is not a replacement for prescription medication, but can be excellent nutritional support for your dietary health plan. We call this SISô (which stands for ëSoy Integrative Supportíô). Revival Soy can be integrated into your current health plan to help you achieve better health.

Can I use progesterone creams, herbal supplements or soy isoflavone pills with Revival?

We know of no reason why you canít enjoy Revival Soy while you are using progesterone cream or other dietary supplements.

Soy has many more benefits than progesterone cream. Visit our Soy Benefits and Research Libary at http://www.revivalsoy.com/whysoy/index.html?pid=3000 for more details.

Please let me know if I can help further.
Best Regards,
Aaron Tabor, MD

Read More About Revival

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Revival Web Site

We have a very good online reference source:
SOY HEALTH LIBRARYwith easy-to-read articles on many health topics

* Read a guest transcript with Dr. Tabor

* Revival is a dietary supplement. These statements have not been evaluated by the Food and Drug Administration. Revival is not intended to diagnose, treat, cure or prevent any disease. The information presented on our web site is not intended to take the place of your personal physician's advice.

Please consult a physician before using if you are pregnant or nursing,taking medication or suffer from chronic disease.

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